Hadzic, Baumann & MCLIN
Table of Contents
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BRIEF HISTORY OF PLT
HEALTH SYSTEM BACKGROUND REQUIREMENTS FOR PLT
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Brain death criteria
Non-heart beating donors
Donor procurement
Managing a scarce resource: Differences in donor allocation across the world
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INDICATIONS AND CONTRAINDICATIONS (and their evolution) - General aspects
(List of diagnoses)
PREPARATION FOR PLT
Medical (immunisations/cardiac/renal/neurological aspects)
Surgical and Radiological aspects
Psychological/Social aspects
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ANAESTHETIC ASPECTS (Risk assessment)
SURGICAL ASPECTS (Choice of donor for PLT, Prevention of thrombosis/anticoagulation)
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SURGICAL TECHNIQUES
Split graft
Living-related
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Auxiliary
Domino
Techniques and present role of hepatocyte transplantation
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STRATEGIES IN IMMUNE SUPPRESSION (Immune ablation, renal-sparing, steroid-sparing)
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- Evolution of transplantation medicine
- Before transplantation
- Paediatric liver transplantation
- Management after Transplantation
INTENSIVE CARE ASPECTS
ANTI-INFECTION STRATEGIES
Viral
Bacterial
Fungal
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EARLY COMPLICATIONS
SURGICAL (biliary, vascular, etc.)
MEDICAL
ROLE OF HISTOLOGY AFTER PLT
ROLE OF RADIOLOGY AND INTERVENTIONAL RADIOLOGY AFTER PLT
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LATE COMPLICATIONS
SURGICAL (graft re-modelling, secondary portal hypertension/shunts)
MEDICAL (recurrent disease post-PLT, de novo AIH, post-transplant lymphoproliferative disease, nephrotoxicity)
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PSYCHOSOCIAL ASPECTS AFTER PLT
(social reintegration, medication adherence, family planning, education)
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PROSPECTS FOR IMMUNE TOLERANCE (possibilities for safe withdrawal of immunosuppression)
TRANSITION TO ADULT SERVICES (smooth handover of care to a different system)
FUTURE REQUIREMENTS