Stoelting Pharmacology Physiology in Anesthetic Practice

xv
CONTENTS
Dedication v
Contributors vii
Foreword to the Sixth Edition xi
Preface to the Sixth Edition xiii
PART I
Basic Principles of Physiology and
Pharmacology
1. Basic Principles of Physiology . . . . . . . . . . . . 1
Pamela Flood • Lisa Wise-Faberowski • Steven L. Shafer
2. Basic Principles of Pharmacology . . . . . . . . 12
Pamela Flood • Steven L. Shafer
PART II
Neurologic System
3. Neurophysiology . . . . . . . . . . . . . . . . . . . . . . 49
Pamela Flood • Cassandra Bailey
4. Inhaled Anesthetics. . . . . . . . . . . . . . . . . . . . 95
Pamela Flood • Steven L. Shafer • Ardin S. Berger
5. Intravenous Sedatives and Hypnotics. . . .150
James P. Rathmell • Albert Dahan
6. Pain Physiology . . . . . . . . . . . . . . . . . . . . . . . 195
Hui Yang • Bihua Bie • Mohamed A. Naguib
7. Opioid Agonists and Antagonists . . . . . . 206
Kenneth C. Cummings III • Mohamed A. Naguib
8. Centrally Acting Nonopioid
Analgesics. . . . . . . . . . . . . . . . . . . . . . . . . . . 246
Chihiro Toda • Mohamed A. Naguib
9. Peripherally Acting Analgesics. . . . . . . . . 257
Chihiro Toda • Mohamed A. Naguib
10. Local Anesthetics . . . . . . . . . . . . . . . . . . . . .272
Kamal Maheshwari • Mohamed A. Naguib
11. Neuromuscular Physiology . . . . . . . . . . . . 305
Mohamed A. Naguib
12. Neuromuscular-Blocking Drugs and
Reversal Agents. . . . . . . . . . . . . . . . . . . . . . .314
Mohamed A. Naguib
13. Neurologically Active Drugs . . . . . . . . . . . 337
Mark Alexander Burbridge • Pamela Flood
PART III
Circulatory System
14. Circulatory Physiology . . . . . . . . . . . . . . . . 359
James Ramsay
15. Cardiac Physiology . . . . . . . . . . . . . . . . . . . 388
Teresa A. Mulaikal • Andrea N. Miltiades
Sumeet Goswami • Bessie Kachulis
16. Renal Physiology . . . . . . . . . . . . . . . . . . . . . . 415
Brian Chang • Jonathan Hastie
17. Intravenous Fluids and Electrolytes. . . . . .431
Emily P. Wang • Jessica Spellman
18. Sympathomimetic Drugs . . . . . . . . . . . . . . 450
Javier Lorenzo
19. Sympatholytics. . . . . . . . . . . . . . . . . . . . . . . . 471
Steven E. Miller
20. Vasodilators. . . . . . . . . . . . . . . . . . . . . . . . . . 500
Thomas J. Krall • James Ramsay
21. Antiarrhythmic Drugs . . . . . . . . . . . . . . . . . . 516
Wendy Smith • James Ramsay
22. Diuretics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 535
Vikram V. Saxena • Maya Jalbout Hastie
23. Lipid-Lowering Drugs . . . . . . . . . . . . . . . . . 545
Peter C. Schmidt
PART IV
Pulmonary System
24. Gas Exchange. . . . . . . . . . . . . . . . . . . . . . . . 553
Alexander Huang • Peter Slinger
25. Respiratory Pharmacology . . . . . . . . . . . . 595
Peter Slinger
26. Acid–Base Disorders . . . . . . . . . . . . . . . . . . .616
Peter Slinger
PART V
Blood and Hemostasis
27. Physiology of Blood and Hemostasis . . . 627
Jerrold H. Levy
28. Blood Products and Blood
Components . . . . . . . . . . . . . . . . . . . . . . . . . 636
Jerrold H. Levy
29. Procoagulants. . . . . . . . . . . . . . . . . . . . . . . . . 651
Jerrold H. Levyxvi Contents
PART VIII
Miscellaneous
41. Antimicrobials, Antiseptics,
Disinfectants, and Management of
Perioperative Infection. . . . . . . . . . . . . . . . .801
Stephanie J. Pan • Pamela Flood
42. Chemotherapeutic Drugs. . . . . . . . . . . . . . 827
Ami K. Patel • Richard D. Urman • James P. Rathmell
43. Psychopharmacologic Drugs . . . . . . . . . . 854
Peter J. van Roessel • Carolyn Rodriguez • Pamela Flood
PART IX
Special Populations
44. Physiology of the Newborn. . . . . . . . . . . . 889
Becky J. Wong • Lisa Wise-Faberowski
45. Maternal and Fetal Physiology and
Pharmacology . . . . . . . . . . . . . . . . . . . . . . . 894
Amy W. Willett • Pamela Flood
46. Physiology and Pharmacology of
the Elderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . 921
Andrea Girnius • Pamela Flood
47. Physiology and Pharmacology of
Resuscitation . . . . . . . . . . . . . . . . . . . . . . . . 935
Michael J. Murray • Sean M. Dennig
Drug Index 945
Subject Index 950
30. Anticoagulants . . . . . . . . . . . . . . . . . . . . . . . 660
Jerrold H. Levy
31. Physiology and Management of
Massive Transfusion . . . . . . . . . . . . . . . . . . 674
Jerrold H. Levy
PART VI
Gastrointestinal System and
Metabolism
32. Gastrointestinal Physiology. . . . . . . . . . . . 683
Michael J. Murray
33. Metabolism . . . . . . . . . . . . . . . . . . . . . . . . . . 697
Michael J. Murray
34. Antiemetics . . . . . . . . . . . . . . . . . . . . . . . . . . 707
Christopher M. Lam • Michael J. Murray
35. Antacids and Gastrointestinal
Motility Drugs. . . . . . . . . . . . . . . . . . . . . . . . . 717
Michael J. Murray
36. Nutrition. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733
Michael J. Murray
PART VII
Endocrine System
37. Normal Endocrine Function . . . . . . . . . . . 753
Priya Patidar • Vivek K. Moitra
38. Drugs that Alter Glucose Regulation . . . 769
Bianca Bromberger • Vivek K. Moitra
39. Drugs for the Treatment of
Hypothyroidism and
Hyperthyroidism . . . . . . . . . . . . . . . . . . . . . 779
Dasun Peramunage • Vivek K. Moitra
40. Other Endocrine Drugs . . . . . . . . . . . . . . . 783
Artem Emple • Vivek K. Moitra

Selected as a Doody's Core Title for 2021! Comprehensive, readable, and clinically oriented, Stoelting’s Pharmacology & Physiology in Anesthetic Practice, Sixth Edition, covers all aspects of pharmacology and physiology that are relevant either directly or indirectly to the anesthetic practice—a challenging topic that is foundational to the practice of anesthesia and essential to master. This systems-based, bestselling text has been thoroughly updated by experts in the field, giving you the detailed information needed to make the most informed clinical decisions about the care of your patients. Offers trainees and practitioners authoritative content on all aspects of pharmacology and physiology that are relevant to anesthesiology. Features up-to-date coverage of new drugs, as well as new findings on the actions and interactions of established drugs. Discusses antimicrobials and chemotherapeutic drugs, as well as special populations such as the newborn, the parturient and fetus, the elderly, and the physiology and pharmacology of resuscitation. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.