Cell Biology

Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods-from single cell RNA sequencing to second generation super resolution fluorescence microscopy-on advancing our understanding.

Table of Contents

 Front Matter/Back Matter/Section Openers
1 Introduction to Cells
2 Evolution of Life on Earth
3 Molecules: Structures and Dynamics
4 Biophysical Principles
5 Macromolecular Assembly
6 Research Strategies
7 Chromosome Organization
8 DNA Packaging in Chromatin and Chromosomes
9 Nuclear Structure and Dynamics
10 Gene Expression
11 Eukaryotic RNA Processing
12 Protein Synthesis and Folding
13 Membrane Structure and Dynamics
14 Membrane Pumps
15 Membrane Carriers
16 Membrane Channels
17 Membrane Physiology
18 Posttranslational Targeting of Proteins
19 Mitochondria, Chloroplasts, Peroxisomes
20 Endoplasmic Reticulum
21 Mechanisms of Vesicular Trafficking
22 Secretory Membrane System and Golgi Appartus
23 Endocytosis and Endosomal Membrane System
24 Processing and Degradation of Cellular Components
25 Plasma Membrane Receptors
26 Protein Hardware for Signaling
27 Second Messengers
28 Integration of Signals
29 Cells of the Extracellular Matrix and Immune System
30 Extracellular Matrix Molecules
31 Cellular Adhesion
32 Intercellular Junctions
33 Connective Tissues
34 Actin and Actin-Binding Proteins
35 Microtubules and Centrosomes
36 Intermediate Filaments
37 Motor Proteins
38 Intracellular Motility
39 Cellular Motility
40 Muscles
41 Introduction to the Cell Cycle
42 G1 Phase and Regulation of Cell Proliferation
43 S Phase and DNA Replications
44 G2 Phase, Responses to DNA Damage, and Control of Entry into Mitosis
45 Mitosis
46 Cytokinesis
47 Meiosis
48 Programmed Cell Death
 Cell SnapShots